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Gfi1b alters histone methylation at target gene promoters and sites of γ-satellite containing heterochromatin
Gfi1b is a 37 kDa nuclear protein with six C(2)H(2) zinc-finger domains that can silence transcription upon binding to specific target gene promoters. Here we show by using a chromatin immunoprecipitation and cloning protocol that Gfi1b also binds to γ-satellite sequences that mainly occur in perice...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1478184/ https://ncbi.nlm.nih.gov/pubmed/16688220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601124 |
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