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From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation
The DNA-binding zinc finger transcription factors Gfi1 and Gfi1b were discovered more than 20 years ago and are recognized today as major regulators of both early hematopoiesis and hematopoietic stem cells. Both proteins function as transcriptional repressors by recruiting histone-modifying enzymes...
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| Veröffentlicht in: | Blood |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4671106/ https://ncbi.nlm.nih.gov/pubmed/26447191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-655043 |
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