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Role of GFI1 in Epigenetic Regulation of MDS and AML Pathogenesis: Mechanisms and Therapeutic Implications

Growth factor independence 1 (GFI1) is a DNA binding zinc finger protein, which can mediate transcriptional repression mainly by recruiting histone-modifying enzymes to its target genes. GFI1 plays important roles in hematopoiesis, in particular by regulating both the function of hematopoietic stem-...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Möröy, Tarik, Khandanpour, Cyrus
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718700/
https://ncbi.nlm.nih.gov/pubmed/31508375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00824
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