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Age-related epigenetic drift in the pathogenesis of MDS and AML

The myelodysplastic syndrome (MDS) is a clonal hematologic disorder that frequently evolves to acute myeloid leukemia (AML). Its pathogenesis remains unclear, but mutations in epigenetic modifiers are common and the disease often responds to DNA methylation inhibitors. We analyzed DNA methylation in...

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מידע ביבליוגרפי
Main Authors: Maegawa, Shinji, Gough, Sheryl M., Watanabe-Okochi, Naoko, Lu, Yue, Zhang, Nianxiang, Castoro, Ryan J., Estecio, Marcos R.H., Jelinek, Jaroslav, Liang, Shoudan, Kitamura, Toshio, Aplan, Peter D., Issa, Jean-Pierre J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975058/
https://ncbi.nlm.nih.gov/pubmed/24414704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.157529.113
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