Age-related epigenetic drift in the pathogenesis of MDS and AML

The myelodysplastic syndrome (MDS) is a clonal hematologic disorder that frequently evolves to acute myeloid leukemia (AML). Its pathogenesis remains unclear, but mutations in epigenetic modifiers are common and the disease often responds to DNA methylation inhibitors. We analyzed DNA methylation in...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Maegawa, Shinji, Gough, Sheryl M., Watanabe-Okochi, Naoko, Lu, Yue, Zhang, Nianxiang, Castoro, Ryan J., Estecio, Marcos R.H., Jelinek, Jaroslav, Liang, Shoudan, Kitamura, Toshio, Aplan, Peter D., Issa, Jean-Pierre J.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2014
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975058/
https://ncbi.nlm.nih.gov/pubmed/24414704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.157529.113
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы