Growth Factor Independence 1b (Gfi1b) Is Important for the Maturation of Erythroid Cells and the Regulation of Embryonic Globin Expression

Growth factor independence 1b (GFI1B) is a DNA binding repressor of transcription with vital functions in hematopoiesis. Gfi1b-null embryos die at midgestation very likely due to defects in erythro- and megakaryopoiesis. To analyze the full functionality of Gfi1b, we used conditionally deficient mic...

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Bibliographic Details
Main Authors: Vassen, Lothar, Beauchemin, Hugues, Lemsaddek, Wafaa, Krongold, Joseph, Trudel, Marie, Möröy, Tarik
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011847/
https://ncbi.nlm.nih.gov/pubmed/24800817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096636
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