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TAZ encodes tafazzin, a transacylase essential for cardiolipin formation and central to the etiology of Barth syndrome

Tafazzin, which is encoded by the TAZ gene, catalyzes transacylation to form mature cardiolipin and shows preference for the transfer of a linoleic acid (LA) group from phosphatidylcholine (PC) to monolysocardiolipin (MLCL) with influence from mitochondrial membrane curvature. The protein contains d...

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Detalhes bibliográficos
Publicado no:Gene
Main Authors: Garlid, Anders O., Schaffer, Calvin T., Kim, Jaewoo, Bhatt, Hirsh, Guevara-Gonzalez, Vladimir, Ping, Peipei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646589/
https://ncbi.nlm.nih.gov/pubmed/31647997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2019.144148
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