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TAZ encodes tafazzin, a transacylase essential for cardiolipin formation and central to the etiology of Barth syndrome
Tafazzin, which is encoded by the TAZ gene, catalyzes transacylation to form mature cardiolipin and shows preference for the transfer of a linoleic acid (LA) group from phosphatidylcholine (PC) to monolysocardiolipin (MLCL) with influence from mitochondrial membrane curvature. The protein contains d...
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| 發表在: | Gene |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7646589/ https://ncbi.nlm.nih.gov/pubmed/31647997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2019.144148 |
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