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TAZ encodes tafazzin, a transacylase essential for cardiolipin formation and central to the etiology of Barth syndrome

Tafazzin, which is encoded by the TAZ gene, catalyzes transacylation to form mature cardiolipin and shows preference for the transfer of a linoleic acid (LA) group from phosphatidylcholine (PC) to monolysocardiolipin (MLCL) with influence from mitochondrial membrane curvature. The protein contains d...

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Dades bibliogràfiques
Publicat a:Gene
Autors principals: Garlid, Anders O., Schaffer, Calvin T., Kim, Jaewoo, Bhatt, Hirsh, Guevara-Gonzalez, Vladimir, Ping, Peipei
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646589/
https://ncbi.nlm.nih.gov/pubmed/31647997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2019.144148
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