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Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy
Tafazzin (TAZ) is a phospholipid transacylase that catalyzes the remodeling of cardiolipin, a mitochondrial phospholipid required for oxidative phosphorylation. Mutations of TAZ cause Barth syndrome, which is characterized by mitochondrial dysfunction and dilated cardiomyopathy, leading to premature...
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| Publicat a: | Autophagy |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502692/ https://ncbi.nlm.nih.gov/pubmed/25919711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1023984 |
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