Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy

Tafazzin (TAZ) is a phospholipid transacylase that catalyzes the remodeling of cardiolipin, a mitochondrial phospholipid required for oxidative phosphorylation. Mutations of TAZ cause Barth syndrome, which is characterized by mitochondrial dysfunction and dilated cardiomyopathy, leading to premature...

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Bibliografiska uppgifter
I publikationen:Autophagy
Huvudupphovsmän: Hsu, Paul, Liu, Xiaolei, Zhang, Jun, Wang, Hong-Gang, Ye, Ji-Ming, Shi, Yuguang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2015
Ämnen:
Basic Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502692/
https://ncbi.nlm.nih.gov/pubmed/25919711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1023984
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