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Identification of new driver and passenger mutations within APOBEC-induced hotspot mutations in bladder cancer
BACKGROUND: APOBEC-driven mutagenesis and functional positive selection of mutated genes may synergistically drive the higher frequency of some hotspot driver mutations compared to other mutations within the same gene, as we reported for FGFR3 S249C. Only a few APOBEC-associated driver hotspot mutat...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Genome Med |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7646471/ https://ncbi.nlm.nih.gov/pubmed/32988402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00781-y |
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