Loading...

Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9

The Rag GTPases (Rags) recruit mTORC1 to the lysosomal membrane in response to nutrients, where it is then activated in response to energy and growth factor availability. The lysosomal folliculin (FLCN) complex (LFC) consists of the inactive Rag dimer, the pentameric scaffold Ragulator, and the FLCN...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Struct Mol Biol
Main Authors: Fromm, Simon A., Lawrence, Rosalie E., Hurley, James H.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644641/
https://ncbi.nlm.nih.gov/pubmed/32868926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0490-9
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!