Nalaganje...

Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes

The mTORC1 complex supports cell growth and proliferation in response to energy levels, growth factors, and nutrients. The Rag guanosine triphosphatases (GTPases) activate mTORC1 in response to amino acids by promoting its redistribution to lysosomes. In this paper, we identify a novel role for Rags...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Martina, Jose A., Puertollano, Rosa
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575543/
https://ncbi.nlm.nih.gov/pubmed/23401004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201209135
Oznake: Označite
Brez oznak, prvi označite!