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Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes
The mTORC1 complex supports cell growth and proliferation in response to energy levels, growth factors, and nutrients. The Rag guanosine triphosphatases (GTPases) activate mTORC1 in response to amino acids by promoting its redistribution to lysosomes. In this paper, we identify a novel role for Rags...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575543/ https://ncbi.nlm.nih.gov/pubmed/23401004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201209135 |
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