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TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes
Lysosomal distribution is linked to the role of lysosomes in many cellular functions, including autophagosome degradation, cholesterol homeostasis, antigen presentation, and cell invasion. Alterations in lysosomal positioning contribute to different human pathologies, such as cancer, neurodegenerati...
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Foilsithe in: | Nat Commun |
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Main Authors: | , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Nature Publishing Group UK
2017
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5691037/ https://ncbi.nlm.nih.gov/pubmed/29146937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01871-z |
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