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Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases
Birt-Hogg-Dubé syndrome, a human disease characterized by fibrofolliculomas (hair follicle tumors) as well as a strong predisposition toward the development of pneumothorax, pulmonary cysts, and renal carcinoma, arises from loss-of-function mutations in the folliculin (FLCN) gene. In this study, we...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787382/ https://ncbi.nlm.nih.gov/pubmed/24081491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307084 |
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