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Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases

Birt-Hogg-Dubé syndrome, a human disease characterized by fibrofolliculomas (hair follicle tumors) as well as a strong predisposition toward the development of pneumothorax, pulmonary cysts, and renal carcinoma, arises from loss-of-function mutations in the folliculin (FLCN) gene. In this study, we...

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Bibliografiska uppgifter
Huvudupphovsmän: Petit, Constance S., Roczniak-Ferguson, Agnes, Ferguson, Shawn M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787382/
https://ncbi.nlm.nih.gov/pubmed/24081491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307084
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