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Alcohol induces TGFβ1 via downregulation of miR-1946a in murine lung fibroblast
Exaggerated transforming growth factor-beta 1 (TGFβ1) expression worsens fibroproliferation following bleomycin-induced lung injury in alcohol-fed mice. MicroRNA (miR)-1946a is predicted to bind to the TGFβ1 3′ untranslated region (UTR), thereby inhibiting its transcription. We hypothesize that alco...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7644620/ https://ncbi.nlm.nih.gov/pubmed/33154445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76148-5 |
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