Circular RNA RORβ regulates TGFβR1 in alcohol-induced fibroblast-to-myofibroblast differentiation

Abstract Alcohol exposure augments the expression and signaling of transforming growth factor-beta (TGFβ), leading to fibroproliferation. We showed that inhibition of TGFβ receptor type 1 (TGFβR1) mitigates the effect of alcohol in the lung. We further demonstrated that alcohol modulates TGFβ signal...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Viranuj Sueblinvong, Xian Fan, Harry Kartmouty-Quintana, Benjamin T. Kopp, Bum-Yong Kang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2025-09-01
Sarja:Scientific Reports
Aiheet:
Alcohol
microRNA
Circular RNA
Circ-RORβ
TGFβ receptor 1
Fibroblast-to-myofibroblast differentiation
Linkit:https://doi.org/10.1038/s41598-025-15040-6
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