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TGF-β1 epigenetically modifies Thy-1 expression in primary lung fibroblasts

Idiopathic pulmonary fibrosis is a progressive lung disease that increases in incidence with age. We identified a profibrotic lung phenotype in aging mice characterized by an increase in the number of fibroblasts lacking the expression of thymocyte differentiation antigen 1 (Thy-1) and an increase i...

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Détails bibliographiques
Publié dans:Am J Physiol Cell Physiol
Auteurs principaux: Neveu, Wendy A., Mills, Stephen T., Staitieh, Bashar S., Sueblinvong, Viranuj
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628935/
https://ncbi.nlm.nih.gov/pubmed/26333597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00086.2015
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