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TGFβ1 Mediates Alcohol-Induced Nrf2 Suppression in Lung Fibroblasts
BACKGROUND: Chronic alcohol ingestion induces the expression of transforming growth factor beta-1(TGFβ1), inhibits nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-mediated activation of the antioxidant response element (ARE), depletes alveolar glutathione pools, and potentiates acute lung injury....
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| Gepubliceerd in: | Alcohol Clin Exp Res |
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| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BlackWell Publishing Ltd
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244649/ https://ncbi.nlm.nih.gov/pubmed/25421510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12563 |
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