Amido-Bridged Nucleic Acid-Modified Antisense Oligonucleotides Targeting SYT13 to Treat Peritoneal Metastasis of Gastric Cancer

Patients with peritoneal metastasis of gastric cancer have dismal prognosis, mainly because of inefficient systemic delivery of drugs to peritoneal tumors. We aimed to develop an intraperitoneal treatment strategy using amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides (ASOs) tar...

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Bibliografski detalji
Izdano u:Mol Ther Nucleic Acids
Glavni autori: Kanda, Mitsuro, Kasahara, Yuuya, Shimizu, Dai, Miwa, Takashi, Umeda, Shinichi, Sawaki, Koichi, Nakamura, Shunsuke, Kodera, Yasuhiro, Obika, Satoshi
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2020
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644579/
https://ncbi.nlm.nih.gov/pubmed/33230476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.10.001
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