Prokineticin 2 via Calcium-Sensing Receptor Activated NLRP3 Inflammasome Pathway in the Testicular Macrophages of Uropathogenic Escherichia coli-Induced Orchitis

Reproductive tract infections contribute to the development of testicular inflammatory lesions, leading to male infertility. Previous research shows that the activation of the NLRP3 inflammasome in orchitis promotes the secretion and maturation of IL-1β and, thus, decreases male fertility. The calci...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Su, Yufang, Zhang, Yuan, Hu, Zhiyong, He, Liting, Wang, Wei, Xu, Jia, Fan, Zunpan, Liu, Chunyan, Zhang, Huiping, Zhao, Kai
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644440/
https://ncbi.nlm.nih.gov/pubmed/33193351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.570872
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