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Corticosterone Enhances the AMPK-Mediated Immunosuppressive Phenotype of Testicular Macrophages During Uropathogenic Escherichia coli Induced Orchitis

Testicular macrophages (TM) play a central role in maintaining testicular immune privilege and protecting spermatogenesis. Recent studies showed that their immunosuppressive properties are maintained by corticosterone in the testicular interstitial fluid, but the underlying molecular mechanisms are...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Zhang, Zhengguo, Jiang, Ziming, Zhang, Yiming, Zhang, Yu, Yan, Yan, Bhushan, Sudhanshu, Meinhardt, Andreas, Qin, Zhihai, Wang, Ming
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752858/
https://ncbi.nlm.nih.gov/pubmed/33363533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.583276
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