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Prokineticin 2 via Calcium-Sensing Receptor Activated NLRP3 Inflammasome Pathway in the Testicular Macrophages of Uropathogenic Escherichia coli-Induced Orchitis

Reproductive tract infections contribute to the development of testicular inflammatory lesions, leading to male infertility. Previous research shows that the activation of the NLRP3 inflammasome in orchitis promotes the secretion and maturation of IL-1β and, thus, decreases male fertility. The calci...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Su, Yufang, Zhang, Yuan, Hu, Zhiyong, He, Liting, Wang, Wei, Xu, Jia, Fan, Zunpan, Liu, Chunyan, Zhang, Huiping, Zhao, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644440/
https://ncbi.nlm.nih.gov/pubmed/33193351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.570872
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