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Activation of the NLRP3 Inflammasome Pathway by Prokineticin 2 in Testicular Macrophages of Uropathogenic Escherichia coli- Induced Orchitis

Infections of the reproductive tract are known to contribute to testicular inflammatory impairment, leading to an increase of pro-inflammatory cytokines such as IL-1β, and a decline in sperm quality. Prokineticin 2 (PK2), a secretory protein, is closely associated with the secretion of pro-inflammat...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Li, Ying, Su, Yufang, Zhou, Ting, Hu, Zhiyong, Wei, Jiajing, Wang, Wei, Liu, Chunyan, Zhang, Huiping, Zhao, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702272/
https://ncbi.nlm.nih.gov/pubmed/31474981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01872
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