Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation

Successful bacterial pathogens produce an array of virulence factors that allow subversion of the immune system and persistence within the host. For example, uropathogenic Escherichia coli strains, such as CFT073, express Toll/IL-1 receptor–containing (TIR-containing) protein C (TcpC), which impairs...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Waldhuber, Anna, Puthia, Manoj, Wieser, Andreas, Cirl, Christine, Dürr, Susanne, Neumann-Pfeifer, Silke, Albrecht, Simone, Römmler, Franziska, Müller, Tina, Zheng, Yunji, Schubert, Sören, Groß, Olaf, Svanborg, Catharina, Miethke, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922710/
https://ncbi.nlm.nih.gov/pubmed/27214553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81916
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