Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation

Successful bacterial pathogens produce an array of virulence factors that allow subversion of the immune system and persistence within the host. For example, uropathogenic Escherichia coli strains, such as CFT073, express Toll/IL-1 receptor–containing (TIR-containing) protein C (TcpC), which impairs...

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Pubblicato in:J Clin Invest
Autori principali: Waldhuber, Anna, Puthia, Manoj, Wieser, Andreas, Cirl, Christine, Dürr, Susanne, Neumann-Pfeifer, Silke, Albrecht, Simone, Römmler, Franziska, Müller, Tina, Zheng, Yunji, Schubert, Sören, Groß, Olaf, Svanborg, Catharina, Miethke, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922710/
https://ncbi.nlm.nih.gov/pubmed/27214553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81916
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