載入...
Bioreductively Activatable Prodrug Conjugates of Combretastatin A-1 and Combretastatin A-4 as Anticancer Agents Targeted Towards Tumor-Associated Hypoxia
The natural products combretastatin A-1 (CA1) and combretastatin A-4 (CA4) function as potent inhibitors of tubulin polymerization and as selective vascular disrupting agents (VDAs) in tumors. Bioreductively activatable prodrug conjugates (BAPCs) can enhance selectivity by serving as substrates for...
Na minha lista:
| 發表在: | J Nat Prod |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7644341/ https://ncbi.nlm.nih.gov/pubmed/32196334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.9b00773 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|