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Synthetic Lethal Drug Combinations Targeting Proteasome and Histone Deacetylase Inhibitors in TP53-Mutated Cancers

BACKGROUND: We have recently published SL-BioDP, a web resource for querying, exploration and visualization of potential synthetic lethal targets and possible synergistic drug combinations for 18 cancer types. METHODS: From our predictive synthetic lethality model used in SL-BioDP, we inferred TP53...

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Detalhes bibliográficos
Publicado no:Arch Cancer Biol Ther
Main Authors: Das, Shaoli, Deng, Xiang, Camphausen, Kevin, Shankavaram, Uma
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644110/
https://ncbi.nlm.nih.gov/pubmed/33163985
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