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SL-BioDP: Multi-Cancer Interactive Tool for Prediction of Synthetic Lethality and Response to Cancer Treatment

Synthetic lethality exploits the phenomenon that a mutation in a cancer gene is often associated with new vulnerability which can be uniquely targeted therapeutically, leading to a significant increase in favorable outcome. DNA damage and survival pathways are among the most commonly mutated network...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Deng, Xiang, Das, Shaoli, Valdez, Kristin, Camphausen, Kevin, Shankavaram, Uma
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895978/
https://ncbi.nlm.nih.gov/pubmed/31671773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111682
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