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SL-BioDP: Multi-Cancer Interactive Tool for Prediction of Synthetic Lethality and Response to Cancer Treatment

Synthetic lethality exploits the phenomenon that a mutation in a cancer gene is often associated with new vulnerability which can be uniquely targeted therapeutically, leading to a significant increase in favorable outcome. DNA damage and survival pathways are among the most commonly mutated network...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Deng, Xiang, Das, Shaoli, Valdez, Kristin, Camphausen, Kevin, Shankavaram, Uma
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895978/
https://ncbi.nlm.nih.gov/pubmed/31671773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111682
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