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DiscoverSL: an R package for multi-omic data driven prediction of synthetic lethality in cancers
SUMMARY: Synthetic lethality is a state when simultaneous loss of two genes is lethal to a cancer cell, while the loss of the individual genes is not. We developed an R package DiscoverSL to predict and visualize synthetic lethality in cancers using multi-omic cancer data. Mutation, copy number alte...
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| Veröffentlicht in: | Bioinformatics |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6378931/ https://ncbi.nlm.nih.gov/pubmed/30059974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty673 |
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