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Pan-Cancer Analysis of Potential Synthetic Lethal Drug Targets Specific to Alterations in DNA Damage Response

Alterations in DNA damage response (DDR) is one of the several hallmarks of cancer. Genomic instability resulting from a disrupted DDR mechanism is known to contribute to cancer progression, and are subjected to radiation, cytotoxic, or more recently targeted therapies with limited success. Syntheti...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Oncol
Main Authors: Das, Shaoli, Camphausen, Kevin, Shankavaram, Uma
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823874/
https://ncbi.nlm.nih.gov/pubmed/31709193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01136
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