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An engineered T cell receptor variant realizes the limits of functional binding modes
T cell receptors (TCRs) orchestrate cellular immunity by recognizing peptides presented by a range of major histocompatibility complex (MHC) proteins. Naturally occurring TCRs bind the composite peptide/MHC surface, recognizing peptides that are structurally and chemically compatible with the TCR bi...
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| Udgivet i: | Biochemistry |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7642186/ https://ncbi.nlm.nih.gov/pubmed/33074657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00689 |
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