A carregar...
Rictor amplification promotes NSCLC cell proliferation through formation and activation of mTORC2 at the expense of mTORC1
Non-small cell lung cancer (NSCLC) is characterized by genomic alterations, yet a targetable mutation has not been discovered in nearly half of all patients. Recent studies have identified amplification of RICTOR, an mTORC2-specific cofactor, as a novel actionable target in NSCLC. mTORC2 is one of t...
Na minha lista:
| Publicado no: | Mol Cancer Res |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7642103/ https://ncbi.nlm.nih.gov/pubmed/32801163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0262 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|