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Small Molecule Induced Toxic Human-IAPP Species Characterized by NMR

In this study, the effect of CurDAc, a water-soluble curcumin derivative, on the formation and stability of amyloid fibers is revealed. CurDAc interaction with amyloid is structurally selective, which is reflected in a strong interference with hIAPP aggregation while showing weaker interactions with...

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Bibliografiska uppgifter
I publikationen:Chem Commun (Camb)
Huvudupphovsmän: Cox, Sarah J., Rodriguez Camargo, Diana C., Lee, Young-Ho, Dubini, Romeo C. A., Rovó, Petra, Ivanova, Magdalena I., Padmini, Vediappen, Reif, Bernd, Ramamoorthy, Ayyalusamy
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641245/
https://ncbi.nlm.nih.gov/pubmed/33006345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cc04803h
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