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Small Molecule Induced Toxic Human-IAPP Species Characterized by NMR
In this study, the effect of CurDAc, a water-soluble curcumin derivative, on the formation and stability of amyloid fibers is revealed. CurDAc interaction with amyloid is structurally selective, which is reflected in a strong interference with hIAPP aggregation while showing weaker interactions with...
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| Publicado no: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7641245/ https://ncbi.nlm.nih.gov/pubmed/33006345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cc04803h |
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