Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

Oligomeric aggregates populated during the aggregation of the Aβ42 peptide have been identified as potent cytotoxins linked to Alzheimer's disease, but the fundamental molecular pathways that control their dynamics have yet to be elucidated. By developing a general approach combining theory, ex...

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Bibliographic Details
Published in:Nat Chem
Main Authors: Michaels, Thomas C. T., Šarić, Andela, Curk, Samo, Bernfur, Katja, Arosio, Paolo, Meisl, Georg, Dear, Alexander J., Cohen, Samuel I. A., Dobson, Christopher M., Vendruscolo, Michele, Linse, Sara, Knowles, Tuomas P. J.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616962/
https://ncbi.nlm.nih.gov/pubmed/32284577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-020-0452-1
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