Intratumoral antigen signaling traps CD8+ T cells to confine exhaustion to the tumor site

Immunotherapy advances have been hindered by difficulties in tracking the behaviors of lymphocytes following antigen signaling. Here we assessed the behavior of T cells active within tumors through the development of the antigen receptor signaling reporter (AgRSR) mouse, fate mapping lymphocytes res...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Immunol
Asıl Yazarlar: Takahashi, Munetomo, So, Tsz Y., Chamberlain-Evans, Vitalina, Hughes, Robert, Yam-Puc, Juan Carlos, Kania, Katarzyna, Ruhle, Michelle, Mann, Tiffeney, Schuijs, Martijn J., Coupland, Paul, Naisbitt, Dean, Halim, Timotheus Y.F., Lyons, Paul A., Lio, Pietro, Roychoudhuri, Rahul, Okkenhaug, Klaus, Adams, David J., Smith, Ken G.C., Jodrell, Duncan I., Chapman, Michael A., Thaventhiran, James E. D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2024
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616235/
https://ncbi.nlm.nih.gov/pubmed/38787961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.ade2094
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller