Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors

β-arrestins (βarrs) are multifunctional proteins involved in signaling and regulation of seven transmembrane receptors (7TMRs), and their interaction is driven primarily by agonist-induced receptor activation and phosphorylation. Here, we present seven cryo–electron microscopy structures of βarrs ei...

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Publicado en:Science
Autores principales: Maharana, Jagannath, Sano, Fumiya K., Sarma, Parishmita, Yadav, Manish K., Duan, Longhan, Stepniewski, Tomasz M., Chaturvedi, Madhu, Ranjan, Ashutosh, Singh, Vinay, Saha, Sayantan, Mahajan, Gargi, Chami, Mohamed, Shihoya, Wataru, Selent, Jana, Chung, Ka Young, Banerjee, Ramanuj, Nureki, Osamu, Shukla, Arun K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2024
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615931/
https://ncbi.nlm.nih.gov/pubmed/38175886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.adj3
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