Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors

β-arrestins (βarrs) are multifunctional proteins involved in signaling and regulation of seven transmembrane receptors (7TMRs), and their interaction is driven primarily by agonist-induced receptor activation and phosphorylation. Here, we present seven cryo–electron microscopy structures of βarrs ei...

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Publicado no:Science
Main Authors: Maharana, Jagannath, Sano, Fumiya K., Sarma, Parishmita, Yadav, Manish K., Duan, Longhan, Stepniewski, Tomasz M., Chaturvedi, Madhu, Ranjan, Ashutosh, Singh, Vinay, Saha, Sayantan, Mahajan, Gargi, Chami, Mohamed, Shihoya, Wataru, Selent, Jana, Chung, Ka Young, Banerjee, Ramanuj, Nureki, Osamu, Shukla, Arun K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2024
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615931/
https://ncbi.nlm.nih.gov/pubmed/38175886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.adj3
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