Short-course combination treatment for experimental chronic Chagas disease

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects millions of people in the Americas and across the world leading to considerable morbidity and mortality. Current treatment options, benznidazole (BNZ) and nifurtimox, offer limited efficacy and often lead to adverse side eff...

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Pubblicato in:Sci Transl Med
Autori principali: González, Silvia, Wall, Richard J., Thomas, John, Braillard, Stephanie, Brunori, Gino, Díaz, Isabel Camino, Cantizani, Juan, Carvalho, Sandra, Castañeda Casado, Pablo, Chatelain, Eric, Cotillo, Ignacio, Fiandor, Jose M., Francisco, Amanda Fortes, Grimsditch, David, Keenan, Martine, Kelly, John M., Kessler, Albane, Luise, Chiara, Lyon, Jon J., MacLean, Lorna, Marco, Maria, Martin, J. Julio, Martinez, Maria S., Paterson, Christy, Read, Kevin D., Santos-Villarejo, Angel, Zuccotto, Fabio, Wyllie, Susan, Miles, Tim J., De Rycker, Manu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2023
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615676/
https://ncbi.nlm.nih.gov/pubmed/38091410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.adg8105
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