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Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas’ disease drug discovery

Chagas’ disease is responsible for significant mortality and morbidity in Latin America. Current treatments display variable efficacy and have adverse side effects, hence more effective, better tolerated drugs are needed. However, recent efforts have proved unsuccessful with failure of the ergostero...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: MacLean, Lorna M., Thomas, John, Lewis, Michael D., Cotillo, Ignacio, Gray, David W., De Rycker, Manu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057682/
https://ncbi.nlm.nih.gov/pubmed/30001347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006612
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