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Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas’ disease drug discovery

Chagas’ disease is responsible for significant mortality and morbidity in Latin America. Current treatments display variable efficacy and have adverse side effects, hence more effective, better tolerated drugs are needed. However, recent efforts have proved unsuccessful with failure of the ergostero...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Negl Trop Dis
Prif Awduron: MacLean, Lorna M., Thomas, John, Lewis, Michael D., Cotillo, Ignacio, Gray, David W., De Rycker, Manu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057682/
https://ncbi.nlm.nih.gov/pubmed/30001347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006612
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