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Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNA(Pyl) pairs
Mutually orthogonal aminoacyl-tRNA synthetase (aaRS)/tRNA pairs provide a foundation for encoding non-canonical amino acids (ncAAs) into proteins, and encoded non-canonical polymer and macrocycle synthesis. Here we discover quintuply orthogonal pyrrolysyl-tRNA synthetase (PylRS)/ tRNA(Pyl) pairs. We...
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| 發表在: | Nat Chem |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2023
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7615293/ https://ncbi.nlm.nih.gov/pubmed/37322102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-023-01232-y |
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