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Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs

Genetically encoding distinct non-canonical amino acids (ncAAs) into proteins synthesized in cells requires mutually orthogonal aminoacyl-tRNA synthetase (aaRS)/tRNA pairs. The pyrrolysyl-tRNA synthetase/(Pyl)tRNA pair from M. mazei (Mm) has been engineered to incorporate diverse ncAAs and is common...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Chem
Prif Awduron: Willis, Julian C. W., Chin, Jason W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055992/
https://ncbi.nlm.nih.gov/pubmed/29807989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0052-5
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