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Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs
Genetically encoding distinct non-canonical amino acids (ncAAs) into proteins synthesized in cells requires mutually orthogonal aminoacyl-tRNA synthetase (aaRS)/tRNA pairs. The pyrrolysyl-tRNA synthetase/(Pyl)tRNA pair from M. mazei (Mm) has been engineered to incorporate diverse ncAAs and is common...
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| Publié dans: | Nat Chem |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6055992/ https://ncbi.nlm.nih.gov/pubmed/29807989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0052-5 |
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