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Engineered triply orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids
Expanding and reprogramming the genetic code of cells for the incorporation of multiple distinct non-canonical amino acids (ncAAs), and the encoded biosynthesis of non-canonical biopolymers, requires the discovery of multiple orthogonal aminoacyltransfer RNA synthetase/tRNA pairs. These pairs must b...
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| Publicat a: | Nat Chem |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116526/ https://ncbi.nlm.nih.gov/pubmed/32472101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-020-0472-x |
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