Retrograde movements determine effective stem cell numbers in the intestine

Morphology and functionality of the epithelial lining differ along the intestinal tract, yet tissue renewal at all sites is driven by stem cells at the base of crypts(1–3). Whether stem cell numbers and behaviour vary at different sites is unknown. Here, we show by intravital microscopy that despite...

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Bibliografski detalji
Izdano u:Nature
Glavni autori: Azkanaz, Maria, Corominas-Murtra, Bernat, Ellenbroek, Saskia I.J., Bruens, Lotte, Webb, Anna T., Laskaris, Dimitrios, Oost, Koen C., Lafirenze, Simona J.A., Annusver, Karl, Messal, Hendrik A., Iqbal, Sharif, Flanagan, Dustin J., Huels, David J., Rojas-Rodríguez, Felipe, Vizoso, Miguel, Kasper, Maria, Sansom, Owen J., Snippert, Hugo J., Liberali, Prisca, Simons, Benjamin D., Katajisto, Pekka, Hannezo, Edouard, van Rheenen, Jacco
Format: Artigo
Jezik:Inglês
Izdano: 2022
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614894/
https://ncbi.nlm.nih.gov/pubmed/35831497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-022-04962-0
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