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Stem cell lineage survival as a noisy competition for niche access

Understanding to what extent stem cell potential is a cell-intrinsic property or an emergent behavior coming from global tissue dynamics and geometry is a key outstanding question of systems and stem cell biology. Here, we propose a theory of stem cell dynamics as a stochastic competition for access...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Corominas-Murtra, Bernat, Scheele, Colinda L. G. J., Kishi, Kasumi, Ellenbroek, Saskia I. J., Simons, Benjamin D., van Rheenen, Jacco, Hannezo, Edouard
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382312/
https://ncbi.nlm.nih.gov/pubmed/32611816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921205117
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