Identity and dynamics of mammary stem cells during branching morphogenesis

During puberty, the mouse mammary gland develops into a highly branched epithelial network. Owing to the absence of exclusive stem cell markers, the location, multiplicity, dynamics and fate of mammary stem cells (MaSCs), which drive branching morphogenesis, are unknown. Here we show that morphogene...

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Udgivet i:Nature
Main Authors: Scheele, Colinda L. G. J., Hannezo, Edouard, Muraro, Mauro J., Zomer, Anoek, Langedijk, Nathalia S. M., van Oudenaarden, Alexander, Simons, Benjamin D., van Rheenen, Jacco
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097610/
https://ncbi.nlm.nih.gov/pubmed/28135720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21046
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