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In Vivo Imaging Reveals Existence of Crypt Fission and Fusion in Adult Mouse Intestine

The intestinal epithelium is a repetitive sheet of crypt and villus units with stem cells at the bottom of the crypts. During postnatal development, crypts multiply via fission, generating 2 daughter crypts from 1 parental crypt. In the adult intestine, crypt fission is observed at a low frequency....

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Détails bibliographiques
Publié dans:Gastroenterology
Auteurs principaux: Bruens, Lotte, Ellenbroek, Saskia I.J., van Rheenen, Jacco, Snippert, Hugo J.
Format: Artigo
Langue:Inglês
Publié: W.B. Saunders 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766054/
https://ncbi.nlm.nih.gov/pubmed/28552620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.05.019
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