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Intestinal crypt homeostasis revealed at single stem cell level by in vivo live-imaging

The rapid turnover of the mammalian intestinal epithelium is supported by stem cells located around the base of the crypt(1). Alongside Lgr5, intestinal stem cells have been associated with various markers, which are expressed heterogeneously within the crypt base region(1-6). Previous quantitative...

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Bibliografiske detaljer
Main Authors: Ritsma, Laila, Ellenbroek, Saskia I.J., Zomer, Anoek, Snippert, Hugo J., de Sauvage, Frederic J., Simons, Benjamin D., Clevers, Hans, van Rheenen, Jacco
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964820/
https://ncbi.nlm.nih.gov/pubmed/24531760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12972
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