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Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodelling and Xbp1
A transient, homeostatic transcriptional response can result in transcriptional memory, programming subsequent transcriptional outputs. Transcriptional memory has great but unappreciated potential to alter animal ageing as animals encounter a multitude of diverse stimuli throughout their lifespan. H...
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| Udgivet i: | Nat Aging |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2022
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614430/ https://ncbi.nlm.nih.gov/pubmed/37118537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43587-022-00312-x |
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