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IgG3 hinge dependent enhancement of intracellular antiviral immunity

Humans have four IgG antibody subclasses that selectively engage immune effector molecules to protect against infections. While IgG1 has been studied in detail and is the subclass of most approved antibody therapeutics, increasing evidence indicate that IgG3 is associated with enhanced protection ag...

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Bibliografische gegevens
Gepubliceerd in:Sci Immunol
Hoofdauteurs: Foss, Stian, Jonsson, Alexandra, Bottermann, Maria, Watkinson, Ruth, Lode, Heidrun E., McAdam, Martin B., Michaelsen, Terje E., Sandlie, Inger, James, Leo C., Andersen, Jan Terje
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2022
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614286/
https://ncbi.nlm.nih.gov/pubmed/35486676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abj1640
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