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IgG3 hinge dependent enhancement of intracellular antiviral immunity

Humans have four IgG antibody subclasses that selectively engage immune effector molecules to protect against infections. While IgG1 has been studied in detail and is the subclass of most approved antibody therapeutics, increasing evidence indicate that IgG3 is associated with enhanced protection ag...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Immunol
Hauptverfasser: Foss, Stian, Jonsson, Alexandra, Bottermann, Maria, Watkinson, Ruth, Lode, Heidrun E., McAdam, Martin B., Michaelsen, Terje E., Sandlie, Inger, James, Leo C., Andersen, Jan Terje
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2022
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614286/
https://ncbi.nlm.nih.gov/pubmed/35486676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abj1640
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