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IgG3 hinge dependent enhancement of intracellular antiviral immunity

Humans have four IgG antibody subclasses that selectively engage immune effector molecules to protect against infections. While IgG1 has been studied in detail and is the subclass of most approved antibody therapeutics, increasing evidence indicate that IgG3 is associated with enhanced protection ag...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Immunol
Prif Awduron: Foss, Stian, Jonsson, Alexandra, Bottermann, Maria, Watkinson, Ruth, Lode, Heidrun E., McAdam, Martin B., Michaelsen, Terje E., Sandlie, Inger, James, Leo C., Andersen, Jan Terje
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2022
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614286/
https://ncbi.nlm.nih.gov/pubmed/35486676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abj1640
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